TargoSpheres® – Technology

principle

The company's proprietary drug delivery technology, TargoSphere®, includes a targeted lipid nanocarrier (LNC) that targets specific cell-surface receptors and has the potential to encapsulate the active ingredients. TargoSpheres® are equipped with so-called "targeting ligands" on their surface – tiny molecules that act like a navigation system, enabling precise binding to target cells.

The development of a specific TS variant with a defined active ingredient depends on the medical application and the respective target receptor on a disease-relevant cell type

Multidimensional benefits

High versatility in drug encapsulation

The TargoSphere® technology is suitable for water-soluble, lipophilic, and amphiphilic active ingredients. It can embed both small molecules (e.g., low-molecule drugs) and larger biologics such as peptides, proteins, RNA, or DNA.

Targeted delivery – maximum effectiveness

The key advantage of the technology lies in the selective delivery of the active ingredient to specific target cells. This achieves maximum therapeutic effect while simultaneously reducing the risk of side effects . This allows for a reduction in the required dosage, improves cost-effectiveness, and promotes sustainable formulation approaches.

Protection & Stability

Encapsulated active ingredients are protected from oxidative stress and enzymatic degradation, leading to improved pharmacokinetics and increased therapeutic benefit.

Wide applicability

Nanoformulations developed using this innovative platform are compatible with various application routes.

  • Pharmaceutical application

    Approach

    As a pioneer in the field of cell-specific nanocarrier technologies, we combine innovative active ingredients, clinically failed drug candidates, and substances with undesirable side effects with our TS® variants. These novel therapeutic approaches and lifecycle management strategies not only enhance product performance but also open up the possibility of generating new intellectual property rights – a strategic advantage in a highly competitive environment.

    Therapy areas

    Our specialized nanoformulation systems address an extremely broad spectrum of medical indications, including:


    • Infectious diseases

    • Chronic inflammatory and autoimmune diseases (CIA)

    • Liver diseases

    • Type 2 diabetes

    These systems are continuously being developed in close collaboration with leading research institutions and industrial partners – with the aim of combining maximum efficiency with the highest therapeutic precision.

  • Further areas of application

    Thanks to its high manufacturing flexibility, the TargoSphere® technology allows for versatile application in a variety of dosage forms. This opens up new possibilities for innovative formulations and individually tailored treatment concepts.

    Oral application

    For oral use, dietary supplements administered in the form of drops, sprays, or oral ampoules are suitable. These dosage forms enable rapid and effective absorption of the active ingredients through the mucous membranes and the digestive tract, thus contributing to optimized bioavailability.

    Topical application

    In the field of external application, the technology is used in cosmetic products such as creams, gels, or serums. It enables the targeted absorption of active ingredients through the skin barrier—ideal for applications in skin care, regeneration, and anti-aging.

    Ophthalmic use

    In addition, TargoSphere® technology also allows the formulation of aqueous nutritional supplements as eye drops. These are particularly suitable for the gentle and targeted delivery of bioactive substances to sensitive areas of the eye.